KAME instllation notes on Mac OS X. Open kame.pro from Qt Creator. MacPorts (assuming placed under /opt/local) versions of gsl, fftw3, libtool-ltdl, libusb, eigen3, pybind11,(libdc1394) are necessary for building. (If needed) Add /opt/local/bin to PATH in the build environment pane of Qt Creator. Do *NOT* install QT from MacPorts. Use the genuine open-source QT. (Note for Qt 6) Qt5 compatibility module must be bundled during installation of Qt. (Re)install Xcode command line tools from developer.apple.com, or xcode-select --install, if ruby.h is not found. Deactivate "Add build library search path..." in the executable environment pane, otherwise, kame crashes just after lauched. (to build universal binary) maybe, fftw-3 requires variants: +universal +clang13 -gfortran Qt creator: project->build step->Additional Arguments->ABIs: check both the ABIs. (Note for NI 488.2) Not working with apple silicon. On x86-64, see https://www.ni.com/ja-jp/support/documentation/bugs/22/ni-488-2-21-5-known-issues.html#